drugset / Trial / NCT03170180

Exploratory Study of Drug Sensitivity Prediction Software (IRCR-DReSS) With Patient-derived Tumor Cells of Metastatic Gastric Cancer

NCT03170180 ↗

Phase 2 Completed 66 enrolled Samsung Medical Center
Non-randomizedParallel-groupOpen-labelTreatment

Summary

1. Metastatic gastric cancer patients who failed standard treatment will be enrolled in this study. 2. After consent form, patient-derived cancer cell will be collected and tested with 3 kinds of drugs (sunitinib, gefitinib, imatinib). 3. Drug sensitivity prediction software (IRCR-DReSS) will present level of sensitivity and patients will be treated with sensitive drugs. 4. Patients will be evaluated every 6 weeks.

Timeline

Start
2017-03-01
Primary completion
2021-10-31
Completion
2021-12-28

Drugs

EvaluationDrugModalityDoseRoute
Subject Gefitinib Small molecule 250 mg —
Subject Imatinib Small molecule 400 mg —
Subject Sunitinib Small molecule 37.5 mg —

Indications