drugset / Trial / NCT03177109
Comparison of Different Desensitizers in Reducing Dentinal Hypersensitivity
RandomizedFactorialSingle-blindTreatment
Summary
This is a single center, randomized control. Sixty eligible subjects will be recruited into 3 study treatment groups (n=20 per group) through computerized randomization. Subjects in group 1 will be treated with 8% arginine containing paste(Colgate® Sensitive Pro-Relief™), group 2 with 5% topical fluoride varnish (Acclean) and group 3 with self-adhesive resin (Seal and protect, Dentsply). The subjects in the study will be evaluated for tactile and air-blast hypersensitivity criteria at baseline, two and four weeks.
Timeline
- Start
- 2017-05-03
- Primary completion
- 2018-12-20
- Completion
- 2018-12-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Fluoride varnish | Other / unclassified | 5 % | — |
| Comparator | L-arginine | Small molecule | 8 % | — |
| Comparator | self-adhesive resin | Unknown | — | — |