drugset / Trial / NCT03179839

The Study of Mindfulness Based Cognitive Therapy and Obsessive-Compulsive Disorder

NCT03179839

Completed 123 enrolled Shanghai Mental Health Center
RandomizedParallel-groupSingle-blindTreatment

Summary

The primary objective of the study is to evaluate the clinical curative effect of MBCT to reduce obsessive and compulsive symptoms. Moreover, the investigators will also explore a MBCT manual for Chinese patients with OCD, which can be widely applied to the clinical practice. There are two parts of the study. The first part is a qualitative research with two pilot MBCT groups. The second part of this study is a single-blind randomized controlled trial with three study arms: one - third of participants receive group mindfulness-based cognitive therapy led by trained MBCT psychotherapists or psychiatrists in addition to medication, one - third of participants receive group psycho-education program and one - third of participants receive drug therapy as usual. All participants have 10 sessions intervention and assessments.

Timeline

Start
2017-01-20
Primary completion
2018-11-20
Completion
2019-07-20

Drugs

EvaluationDrugModalityDoseRoute
Comparator Fluvoxamine Unknown 50 mg
Comparator Sertraline Small molecule 50 mg