drugset / Trial / NCT03180710

A Trial to Investigate the Dose-linearity of BioChaperone® Combo 75/25 and the Safety at Three Different Doses in Subjects With Type 2 Diabetes

NCT03180710

Phase 1 Completed 32 enrolled Adocia
RandomizedCrossoverTriple-blindTreatment

Summary

This is a bicentric, double-blinded, randomised, four-period crossover phase 1 trial, using automated 30-hour euglycemic clamp in subjects with type 2 diabetes mellitus.

Timeline

Start
2017-06-06
Primary completion
2017-08-28
Completion
2017-12-21

Drugs

EvaluationDrugModalityDoseRoute
Subject BioChaperone® Combo 75/25 Unknown 0.6 iu/kg Subcutaneous
Subject BioChaperone® Combo 75/25 Unknown 0.8 iu/kg Subcutaneous
Subject BioChaperone® Combo 75/25 Unknown 1 iu/kg Subcutaneous
Comparator Humalog® Mix25 Protein / enzyme biologic 0.8 iu/kg