drugset / Trial / NCT03184558

Bemcentinib (BGB324) in Combination With Pembrolizumab in Patients With TNBC

NCT03184558

Phase 2 Terminated 29 enrolled BerGenBio ASA Merck Sharp & Dohme LLC · collab
NaSingle-groupOpen-labelTreatment

Summary

This is an open label, single arm, multi-centre phase II study to assess the anti-tumour activity and safety of bemcentinib (BGB324) in combination with pembrolizumab in participants with previously treated, locally advanced and unresectable, or metastatic TNBC or TN-IBC. The primary objective is objective response rate.

Timeline

Start
2017-07-26
Primary completion
2018-08-20
Completion
2018-08-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Bemcentinib Small molecule 200 mg Oral
Subject Pembrolizumab Monoclonal antibody 200 mg Intravenous