drugset / Trial / NCT03189498

A Study to Evaluate the Effect of Renal Impairment on the Pharmacokinetics of JNJ-64041575 in Adult Participants With Various Degrees of Renal Function

NCT03189498

Phase 1 Completed 38 enrolled Janssen Pharmaceutica N.V., Belgium
Non-randomizedParallel-groupOpen-labelOther

Summary

The primary purpose of this study is to evaluate the pharmacokinetic (PK) and systemic exposure of JNJ-63549109 and JNJ-64167896 after a single oral dose of JNJ-64041575 in adult participants with various degrees of renal function (mildly, moderately, or severely impaired, or end-stage renal disease \[ESRD\] with or without hemodialysis) compared to adult participants with normal renal function.

Timeline

Start
2017-07-11
Primary completion
2017-12-06
Completion
2017-12-06

Drugs

EvaluationDrugModalityDoseRoute
Subject JNJ-64041575 Unknown 1000 mg Oral