Effects of Canagliflozin on Intravascular Volume and Hemodynamics

Summary

RESEARCH HYPOTHESIS * In subjects with T2DM and HF, effect of canagliflozin will be superior to placebo for the change from baseline in PCWP after a single dose (6 hours post-dose) and after 4 weeks. * Treatment with canagliflozin will be well tolerated over 4 weeks.

Timeline

Start

2017-09-01

Primary completion

2018-08-01

Completion

2018-08-01

Drugs

Indications