A Double Blind Randomised Placebo-controlled Trial to Assess the Role of Iron Repletion in Glucose Homeostasis.

NCT03191201 ↗

Phase 4 Terminated 32 enrolled Prof Gérard WAEBER Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland · collab Centre Hospitalier Universitaire Vaudois · collab University of Lausanne · collab

RandomizedParallel-groupDouble-blindOther

Summary

In this study the investigators aim at addressing potential relationships between iron stores and glucose homeostasis. Iron (i.e. Ferric Carboxymaltose) will be perfused to pre-menopausal, iron-deficient non-anaemic women suffering from a chronic fatigue syndrome and parameters related to glucose homeostasis, parameters related to metabolic syndrome and inflammation will be measured before and after the intervention.

Timeline

Start: 2017-06-21
Primary completion: 2020-03-09
Completion: 2020-03-09

Publications

Jaccard E, Seyssel K, Gouveia A, Vergely C, Baratali L, Gubelmann C, Froissart M, Favrat B, Marques-Vidal P, Tappy L, Waeber G. Effect of acute iron infusion on insulin secretion: A randomized, double-blind, placebo-controlled trial. EClinicalMedicine. 2022 May 6;48:101434. doi: 10.1016/j.eclinm.2022.101434. eCollection 2022 Jun.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Ferric carboxymaltose	Other / unclassified	1000 mg	Intravenous

A Double Blind Randomised Placebo-controlled Trial to Assess the Role of Iron Repletion in Glucose Homeostasis.

Summary

Timeline

Publications

Drugs

Indications