Effect of an H1 Receptor Antagonist on Exercise Performance in Hypoxia

Summary

This study seeks to determine whether a simple, single intervention of Cetirizine / Zyrtec® use can improve exercise performance of active individuals when acutely exposed to altitude. For this project, healthy subjects will perform steady state and progressive work rate exercise, endurance performance time trials, and repeated sprint performance time trials in the laboratory at a simulated altitude of 3000m (9900ft) after dosing with 10 mg of Cetirizine or a placebo in a repeated measures design.

Timeline

Start

2017-08-31

Primary completion

2018-06-06

Completion

2018-06-06

Drugs

Indications