Impact of Hepatitis B Vaccination on HBs Antigenemia

Summary

* HBV is not curable with persistent HBsAg even after the disappearance of HBV DNA. * HBsAg \> 1000 IU/ml is associated with the risk of virological recurrence and HCC. * There is an impaired immune response to HBsAg and HBV vaccine is an easily available, cost-effective, non-harmful method of stimulating immunity.

Timeline

Start

2011-08-01

Primary completion

2015-10-01

Completion

2015-10-01

Publications

• Shaaban Hanafy A. Impact of hepatitis B vaccination on HBsAg kinetics, interferon-inducible protein 10 level and recurrence of viremia. Cytokine. 2017 Nov;99:99-105. doi: 10.1016/j.cyto.2017.08.002. Epub 2017 Aug 10.

Drugs

Indications