Effects of Repeated Doses of Lu AF35700 on Drug Metabolizing Enzymes

Phase 1 Completed 24 enrolled H. Lundbeck A/S

NaSingle-groupOpen-labelTreatment

This study will help determine which types of drugs that may interact with Lu AF35700

Evaluation	Drug	Modality	Dose	Route
Subject	Caffeine	Small molecule	200 mg	Oral
Subject	Dextromethorphan	Unknown	30 mg	Oral
Subject	Lu AF35700	Unknown	10 mg	Oral
Subject	Midazolam	Small molecule	0.025 mg/kg	Oral
Subject	Midazolam	Small molecule	4 mg	Oral
Subject	Omeprazole	Other / unclassified	40 mg	Oral