drugset / Trial / NCT03196180

Topical Fluorouracil and Imiquimod in Treating Patients With High-Grade Cervical Intraepithelial Neoplasia

NCT03196180

Phase 0 Completed 13 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

This early phase I clinical trial studies the side effects of topical fluorouracil and imiquimod ointment in treating patients with high-grade cervical intraepithelial neoplasia. Topical fluorouracil may kill precancerous cells. Imiquimod ointment may stimulate the immune system. Applying topical fluorouracil and imiquimod ointment may cause fewer side effects and may be a better way to treat patients with precancerous cervical lesions.

Timeline

Start
2019-10-15
Primary completion
2020-11-04
Completion
2024-08-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Imiquimod Other / unclassified Other
Subject fluorouracil Small molecule Other