drugset / Trial / NCT03203447

Suprachoroidal Injection of Triamcinolone Acetonide With IVT Anti-VEGF in Subjects With Macular Edema Following RVO

NCT03203447

Phase 3 Terminated 325 enrolled Clearside Biomedical, Inc.
RandomizedParallel-groupTriple-blindTreatment

Summary

This Phase 3, multicenter, randomized, masked, controlled, parallel group study is designed to demonstrate that suprachoroidal (SC) CLS-TA administered with intravitreal (IVT) anti-VEGF agent in subjects with treatment naive RVO is superior to IVT anti-VEGF agent used alone.

Timeline

Start
2018-03-05
Primary completion
2018-12-18
Completion
2018-12-18

Drugs

EvaluationDrugModalityDoseRoute
Comparator Bevacizumab Monoclonal antibody 1.25 mg Intravitreal
Comparator CLS-TA Unknown 4 mg Other
Comparator Ranibizumab Monoclonal antibody 0.5 mg Intravitreal