Medication Development for Opioid and Alcohol Abuse

Summary

The present proposal will evaluate the ability of gabapentin maintenance to reduce the abuse liability of alcohol, oxycodone, and alcohol in combination with oxycodone in participants with both Opioid Use Disorder and Alcohol Use Disorder.

Timeline

Start

2017-08-01

Primary completion

2021-06-30

Completion

2021-12-30

Publications

• Castillo F, Harris HM, Lerman D, Bisaga A, Nunes EV, Zhang Z, Wall M, Comer SD. Clinical Implications of the Relationship Between Naltrexone Plasma Levels and the Subjective Effects of Heroin in Humans. J Addict Med. 2024 Mar-Apr 01;18(2):110-114. doi: 10.1097/ADM.0000000000001247. Epub 2023 Dec 20.

Drugs

Indications