drugset / Trial / NCT03212430
The Effect of Intravenous L-kynurenine (LKYN) on Cerebral Hemodynamics in Healthy Volunteers
Non-randomizedCrossoverDouble-blindOther
Summary
To measure the cerebral hemodynamic effect of L-kynurenine.
Timeline
- Start
- 2017-03-01
- Primary completion
- 2019-01-20
- Completion
- 2019-01-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | L-kynurenine | Small molecule | 50 ug/kg | Intravenous |
| Subject | L-kynurenine | Small molecule | 100 ug/kg | Intravenous |
| Subject | L-kynurenine | Small molecule | 150 ug/kg | Intravenous |
| Subject | L-kynurenine | Small molecule | 300 ug/kg | Intravenous |
| Subject | L-kynurenine | Small molecule | 500 ug/kg | Intravenous |
| Subject | L-kynurenine | Small molecule | 1 mg/kg | Intravenous |
| Subject | L-kynurenine | Small molecule | 5 mg/kg | Intravenous |