drugset / Trial / NCT03223103

Safety and Immunogenicity of Personalized Genomic Vaccine and Tumor Treating Fields (TTFields) to Treat Glioblastoma

NCT03223103

Phase 1 Active not recruiting 13 enrolled Adilia Hormigo NovoCure Ltd. · collab
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to use precision medicine in the form of a vaccine, a mutation-derived tumor antigen vaccine (MTA-based vaccine) in combination with standard care treatment of glioblastoma (GBM) and Tumor Treating Fields (TTFields). The study is designed to determine whether this treatment combination is well tolerated and safe.

Timeline

Start
2018-03-01
Primary completion
2029-05-12
Completion
2029-05-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Hiltonol Other / unclassified 100 ug
Subject Neoantigen Peptides Vaccine

Indications