drugset / Trial / NCT03223454
Human Amniotic Epithelial Cells for Asherman's Syndrome
Phase 1
Unknown
50 enrolled
The Second Affiliated Hospital of Chongqing Medical University
Shanghai iCELL Biotechnology Co., Ltd, Shanghai, China · collab
RandomizedParallel-groupDouble-blindTreatment
Summary
This project aims to investigate the safety and effectiveness of human amniotic epithelial cells in the treatment of the severe refractory Asherman's syndrome.
Timeline
- Start
- 2017-10
- Primary completion
- 2019-09
- Completion
- 2021-03
Publications
- Background Yu D, Wong YM, Cheong Y, Xia E, Li TC. Asherman syndrome--one century later. Fertil Steril. 2008 Apr;89(4):759-79. doi: 10.1016/j.fertnstert.2008.02.096.
- Background Ilancheran S, Moodley Y, Manuelpillai U. Human fetal membranes: a source of stem cells for tissue regeneration and repair? Placenta. 2009 Jan;30(1):2-10. doi: 10.1016/j.placenta.2008.09.009. Epub 2008 Nov 7.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | hAECs | Cell therapy | 1e+08 cells | Intravenous |