drugset / Trial / NCT03224104
Multi-kinase Inhibitor TG02 (TG02) in Elderly Newly Diagnosed or Adult Relapsed Patients With Anaplastic Astrocytoma or Glioblastoma.
Phase 1
Completed
71 enrolled
European Organisation for Research and Treatment of Cancer - EORTC
Tragara Pharmaceuticals, Inc. · collab
Non-randomizedParallel-groupOpen-labelTreatment
Summary
This is a three parallel cohort, open-labeled, non-randomized, multicenter study. All three cohorts will enroll independently.
Timeline
- Start
- 2018-06-12
- Primary completion
- 2022-05-05
- Completion
- 2022-05-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Temozolomide | Small molecule | 150 mg/m2 | — |
| Subject | Temozolomide | Small molecule | 200 mg/m2 | — |
| Subject | Zotiraciclib | Small molecule | 150 mg | — |
| Subject | Zotiraciclib | Small molecule | 200 mg | — |
| Subject | Zotiraciclib | Small molecule | 250 mg | — |