drugset / Trial / NCT03224819

Study of Emerfetamab (AMG 673) in Adults With Relapsed/Refractory Acute Myeloid Leukemia (AML)

NCT03224819 ↗

Phase 0 Terminated 46 enrolled Amgen
Non-randomizedSequentialOpen-labelTreatment

Summary

The primary objectives of this study are to evaluate the safety and tolerability of emerfetamab in adults with relapsed/refractory acute myeloid leukemia (AML) and to estimate the maximum tolerated dose (MTD) and/or a biologically active dose (eg, recommended phase 2 dose \[RP2D\]).

Timeline

Start
2017-09-07
Primary completion
2020-12-28
Completion
2020-12-28

Outcome

Outcome not reported

Stopped: “Priortization of other Programs”

Drugs

EvaluationDrugModalityDoseRoute
Subject Emerfetamab Monoclonal antibody 0.05 ug Intravenous
Subject Emerfetamab Monoclonal antibody 72 ug Intravenous