drugset / Trial / NCT03236584
Tenofovir Monotherapy in Patients With Chronic Hepatitis B Patients Who Had Achieved Complete Viral Suppression on Lamivudine Plus Adefovir
RandomizedParallel-groupOpen-labelTreatment
Summary
Little is known about efficacy of switching to tenofovir monotherapy for lam-resistant chronic hepatitis B patients who achieved a complete virological response to lamivudine plus adefovir. This study was to investigate the efficacy of switching to tenofovir monotherapy for lamivudine -resistant chronic hepatitis B patients with undetectable hepatitis B virus DNA while on lamivudine plus adefovir combination therapy
Timeline
- Start
- 2015-09-01
- Primary completion
- 2018-03-30
- Completion
- 2019-03-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Adefovir | Unknown | — | — |
| Comparator | Lamivudine | Other / unclassified | — | — |
| Subject | Tenofovir disoproxil fumarate | Small molecule | — | — |
Indications
No indication recorded.