drugset / Trial / NCT03237416
Drug-drug-interaction Study to Assess the Effect of Darolutamide on the Pharmacokinetics of Probe Substrates of CYP3A4 and P-gp in Healthy Male Volunteers
NaSingle-groupOpen-labelOther
Summary
Evaluate the effect of darolutamide on the pharmacokinetics of a probe CYP3A4 substrate and Pgp substrate
Timeline
- Start
- 2017-08-02
- Primary completion
- 2017-10-05
- Completion
- 2017-12-18
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dabigatran etexilate | Unknown | 75 mg | — |
| Subject | Darolutamide | Other / unclassified | 600 mg | — |
| Subject | Midazolam | Small molecule | 1 mg | — |