drugset / Trial / NCT03238157
Steroids for Early Treatment of Radiation Retinopathy
RandomizedParallel-groupOpen-labelTreatment
Summary
Radiation retinopathy is a known complication of ocular radiation therapy. To date there is no known effective treatment. In addition to their anti-vascular endothelial growth factor (VEGF) properties, corticosteroids decrease the retinal capillary permeability by increasing the activity/density of tight junctions and acute inflammatory effects of radiation in various tissues.
Timeline
- Start
- 2022-02-01
- Primary completion
- 2022-09-01
- Completion
- 2022-09-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | fluocinolone acetonide | Small molecule | — | — |