drugset / Trial / NCT03238157

Steroids for Early Treatment of Radiation Retinopathy

NCT03238157

Phase 2/3 Withdrawn The Cleveland Clinic
RandomizedParallel-groupOpen-labelTreatment

Summary

Radiation retinopathy is a known complication of ocular radiation therapy. To date there is no known effective treatment. In addition to their anti-vascular endothelial growth factor (VEGF) properties, corticosteroids decrease the retinal capillary permeability by increasing the activity/density of tight junctions and acute inflammatory effects of radiation in various tissues.

Timeline

Start
2022-02-01
Primary completion
2022-09-01
Completion
2022-09-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator fluocinolone acetonide Small molecule