A Multiple-Dose Study of Intravenous BNZ132-1-40 in Healthy Adult Subjects

Summary

This study is a single-center, randomized, single-blind, placebo (PBO)-controlled, multiple-dose study to characterize the safety, tolerability, PK, and PD of IV BNZ-1 administered to healthy adult subjects once weekly (QW) for 4 doses or once every other week (QOW) for 3 doses. Five cohorts of 6 subjects randomized 5 BNZ-1:1 PBO are planned to be enrolled in the trial. Participants will be followed for 4 weeks after the last dose for safety monitoring, and collection of PK and PD samples.

Timeline

Start

2017-10-30

Primary completion

2018-02-15

Completion

2018-03-08

Drugs

Indications

No indication recorded.