drugset / Trial / NCT03241199

The Efficacy and Safety of Induction-Maintenance Protocol for Patients With Chronic Myelogenous Leukaemia

NCT03241199 ↗

Phase 2 Unknown 15 enrolled The University of Hong Kong
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this pilot study is to investigate whether some patients who were started on a 2G-TKI as first-line treatment can be safely switched to imatinib, a first-generation TKI, while maintaining or even deepening the molecular response as a cost-effective treatment. Eligible patients will be switched to imatinib 400mg daily, with regular molecular monitoring.

Timeline

Start
2017-08-01
Primary completion
2020-06-13
Completion
2021-01-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Imatinib Small molecule 400 mg —