Efficacy of Rapamycin in the Treatment of Cervico-facial Lymphatic Malformations

Summary

To evaluate the efficacy of Rapamycin in extended cervicofacial lymphatic malformations in pediatric patients. Rapamycin is administered oral for a 6 month period. The success rate is determined by volume reduction superior to 1/5e of the initial volume measured by MRI, impact on QOL and reduction of bleeding in case of mucosal involvement.

Timeline

Start

2018-06-25

Primary completion

2027-02

Completion

2027-02

Drugs

Indications