drugset / Trial / NCT03243630

Effects of Flavors on Nicotine Reinforcement in Smokers

NCT03243630

RandomizedCrossoverDouble-blindHealth-services research

Summary

To examine the acute reinforcing effects of menthol, a fruit flavor (green apple) or a fruit flavor plus menthol, alone or in combination with nicotine in smokers. Flavors will be administered by inhalation via electronic cigarettes (e-cigarettes) and nicotine will be administered intravenously. The reinforcing drug effects will be measured with the drug effects questionnaire (DEQ).

Timeline

Start
2018-04-23
Primary completion
2018-12-19
Completion
2019-01-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Nicotine Unknown 0.25 mg/kg Intravenous
Comparator Nicotine Unknown 0.5 mg/kg Intravenous

Indications