drugset / Trial / NCT03243630
Effects of Flavors on Nicotine Reinforcement in Smokers
RandomizedCrossoverDouble-blindHealth-services research
Summary
To examine the acute reinforcing effects of menthol, a fruit flavor (green apple) or a fruit flavor plus menthol, alone or in combination with nicotine in smokers. Flavors will be administered by inhalation via electronic cigarettes (e-cigarettes) and nicotine will be administered intravenously. The reinforcing drug effects will be measured with the drug effects questionnaire (DEQ).
Timeline
- Start
- 2018-04-23
- Primary completion
- 2018-12-19
- Completion
- 2019-01-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Nicotine | Unknown | 0.25 mg/kg | Intravenous |
| Comparator | Nicotine | Unknown | 0.5 mg/kg | Intravenous |