drugset / Trial / NCT03249285
Pharmacogenomics of Hypertension Personalized Medicine (PGX-HT)
RandomizedParallel-groupOpen-labelTreatment
Summary
This is a pharmacogenomic prospective , four-arms, parallel groups, active comparator controlled study in essential hypertensive patients never treated before. Each patient will be genotyped for SNPs (single nucleotide polymorphism) in preliminary genetic profiles and will be treated according to their genetic profile with Peri (Perindopril) 4 mg or HCTZ ( hydrochlorothiazide) 12.5 mg.
Timeline
- Start
- 2016-03
- Primary completion
- 2018-03
- Completion
- 2018-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Hydrochlorothiazide | Unknown | 25 mg | Oral |
| Subject | Peri | Unknown | 8 mg | Oral |