drugset / Trial / NCT03249285

Pharmacogenomics of Hypertension Personalized Medicine (PGX-HT)

NCT03249285

Phase 3 Unknown 300 enrolled Ospedale San Raffaele
RandomizedParallel-groupOpen-labelTreatment

Summary

This is a pharmacogenomic prospective , four-arms, parallel groups, active comparator controlled study in essential hypertensive patients never treated before. Each patient will be genotyped for SNPs (single nucleotide polymorphism) in preliminary genetic profiles and will be treated according to their genetic profile with Peri (Perindopril) 4 mg or HCTZ ( hydrochlorothiazide) 12.5 mg.

Timeline

Start
2016-03
Primary completion
2018-03
Completion
2018-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Hydrochlorothiazide Unknown 25 mg Oral
Subject Peri Unknown 8 mg Oral