drugset / Trial / NCT03249298

Fluid Optimization With Crystalloids and Colloids in Neurosurgery

NCT03249298

Completed 80 enrolled University Medical Centre Ljubljana
RandomizedParallel-groupOpen-labelTreatment

Summary

Fluid optimization in neurosurgical patients has an important impact on preservation of cerebral perfusion pressure and minimization of cerebral oedema during and after the craniotomy. The investigators would like to know if crystalloids or colloids are equally useful for goal directed therapy in this patients. The investigators will record haemodynamic stability, volume loading and postoperative complications and compare two groups of patients. One group will be optimised with crystalloids and the second with colloids. The investigators will compare also hospital stay and mortality in the two groups.

Timeline

Start
2017-01
Primary completion
2017-12
Completion
2018-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Sterofundin Unknown 250 ml
Comparator hydroxyethyl starch Other / unclassified 250 ml

Indications

No indication recorded.