drugset / Trial / NCT03252808

Phase I Study of TBI-1401(HF10) Plus Chemotherapy in Patients with Unresectable Pancreatic Cancer.

NCT03252808

Phase 1 Active not recruiting 36 enrolled Takara Bio Inc.
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to determine the recommended dose of TBI-1401(HF10) treatment in combination with chemotherapy (Gemcitabine + Nab-paclitaxel or TS-1) in patients with stage III or IV unresectable pancreatic cancer.

Timeline

Start
2017-09-25
Primary completion
2020-02-19
Completion
2035-03-31

Drugs

EvaluationDrugModalityDoseRoute
Subject CANERPATUREV Other / unclassified 1e+06 unknown Other
Subject CANERPATUREV Other / unclassified 1e+07 unknown Other
Background Gemcitabine Small molecule 1000 mg/m2 Intravenous
Background Paclitaxel Small molecule 125 mg/m2 Intravenous
Background S-1 Small molecule 40 mg/m2 Oral
Background S-1 Small molecule 60 mg/m2 Oral