Methoxyflurane vs Standard Analgesic Treatment for Trauma Pain in Spanish Emergency Units

Phase 3 Completed 310 enrolled Mundipharma Pharmaceuticals S.L. Spanish Clinical Research Network - SCReN · collab Spanish Society for Emergency Medicine (SEMES) · collab

RandomizedParallel-groupOpen-labelTreatment

Summary

Clinical trial to compare pain relief between methoxyflurane and any analgesic treatment used in usual clinical practice, in patients with trauma and associated pain, treated in Spanish emergency units.

Timeline

Start: 2017-07-07
Primary completion: 2018-03-06
Completion: 2018-07-31

Publications

Borobia AM, Collado SG, Cardona CC, Pueyo RC, Alonso CF, Torres IP, Gonzalez MC, Casal Codesido JR, Betegon MA, Barcela LA, Andicoechea AO, Testa AF, Colina JT, Dorribo AC, Del Arco Galan C, Martinez Avila JC, Lugilde ST, Carcas Sansuan AJ; InMEDIATE Investigators Group. Inhaled Methoxyflurane Provides Greater Analgesia and Faster Onset of Action Versus Standard Analgesia in Patients With Trauma Pain: InMEDIATE: A Randomized Controlled Trial in Emergency Departments. Ann Emerg Med. 2020 Mar;75(3):315-328. doi: 10.1016/j.annemergmed.2019.07.028. Epub 2019 Oct 14.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Methoxyflurane	Small molecule	3 ml	Inhaled

Indications

No indication recorded.