Group A Pharyngitis in Children: The GASPARD Study

Phase 4 Unknown 360 enrolled Klara Posfay-Barbe Gertrude Von Meissner Foundation · collab Recherche et Développement des HUG · collab Société académique de Genève · collab

RandomizedParallel-groupQuadruple-blindTreatment

Summary

Evaluate the necessity to treat with antibiotics GAS pharyngitis in children in Switzerland. The null hypothesis is that antibiotic treatment is not necessary for GAS pharyngitis in this population.

Timeline

Start: 2017-01-27
Primary completion: 2018-12-31
Completion: 2018-12-31

Publications

Gualtieri R, Verolet C, Mardegan C, Papis S, Loevy N, Asner S, Rohr M, Llor J, Heininger U, Lacroix L, Pittet LF, Posfay-Barbe KM. Amoxicillin vs. placebo to reduce symptoms in children with group A streptococcal pharyngitis: a randomized, multicenter, double-blind, non-inferiority trial. Eur J Pediatr. 2024 Nov;183(11):4773-4782. doi: 10.1007/s00431-024-05705-1. Epub 2024 Aug 31.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Amoxicillin	Other / unclassified	50 mg/kg	Oral

Group A Pharyngitis in Children: The GASPARD Study

Summary

Timeline

Publications

Drugs

Indications