drugset / Trial / NCT03265223

Ropivacaine Use Intraincisionally Versus Intraperitoneally for Post-Laparoscopic Cholecystectomy Pain

NCT03265223 ↗

Phase 4 Completed 353 enrolled Jawaharlal Nehru Medical College
RandomizedParallel-groupTriple-blindTreatment

Summary

Pain still remains a limiting factor in early discharge of patients undergoing laparoscopic cholecystectomy. Almost all earlier studies done to compare the efficacy of local anaesthetics used intraperitoneally as compared to intraincisionally used equal amounts of drugs at the two locations, usually 10-20 ml. Using this large amount of drug in the small space of intraincisional location as compared to similar amount of drug in large intraperitoneal space created an inadvertent bias in favor of patients receiving the drug intraincisionally so such patients naturally experienced less pain. The investigators decided to standardize the drug used at these two locations as 1ml/cm and conduct a new study comparing the effects of drugs in relieving pain when used at these two locations.

Timeline

Start
2014-04-01
Primary completion
2017-03-31
Completion
2017-08-15

Drugs

EvaluationDrugModalityDoseRoute
Comparator Ropivacaine Other / unclassified 3 ml Intravenous
Comparator Ropivacaine Other / unclassified 20 ml Intravenous

Indications

No indication recorded.