Effect of Duloxetine on Opioid Use After Total Knee Arthroplasty

Summary

Post-discharge pain after total knee arthroplasty remains problematic; many patients have excessive pain at the 2 week time point (and often thereafter). Reduction in opioid use has become a national goal, due to the 'epidemic' in opioid misuse. In addition to enrolling non-opioid users, we will enroll up to 15 chronic opioid users.

Timeline

Start

2017-09-28

Primary completion

2020-12-03

Completion

2021-02-19

Drugs

Indications