drugset / Trial / NCT03276832
Imiquimod and Pembrolizumab in Treating Patients With Stage IIIB-IV Melanoma
NaSingle-groupOpen-labelTreatment
Summary
This pilot early phase I trial studies the side effects and how well imiquimod and pembrolizumab work in treating patients with stage IIIB-IV melanoma. Imiquimod may stimulate the immune system. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving imiquimod and pembrolizumab may work better at treating melanoma.
Timeline
- Start
- 2017-12-20
- Primary completion
- 2019-10-15
- Completion
- 2019-10-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Imiquimod | Other / unclassified | — | Topical |
| Subject | Pembrolizumab | Monoclonal antibody | — | Intravenous |