drugset / Trial / NCT03276832

Imiquimod and Pembrolizumab in Treating Patients With Stage IIIB-IV Melanoma

NCT03276832

Phase 0 Completed 7 enrolled Mayo Clinic
NaSingle-groupOpen-labelTreatment

Summary

This pilot early phase I trial studies the side effects and how well imiquimod and pembrolizumab work in treating patients with stage IIIB-IV melanoma. Imiquimod may stimulate the immune system. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving imiquimod and pembrolizumab may work better at treating melanoma.

Timeline

Start
2017-12-20
Primary completion
2019-10-15
Completion
2019-10-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Imiquimod Other / unclassified Topical
Subject Pembrolizumab Monoclonal antibody Intravenous