Determination of Propofol Target Concentration for Young and Elderly by Suppression Rate Analysis

Summary

Propofol's dose-response curve is know for the average adult but propofol's plasmatic concentration under total intravenous anesthesia differences between young and elderly must be modeled. Adaptative clinical trial (Dixon's Up and Down) for determination of ED95% of propofol concentration for hypnosis under general anesthesia for young and elderly adults.

Timeline

Start

2017-01-30

Primary completion

2017-01-30

Completion

2017-01-30

Outcome

Outcome not reported

Stopped: “Local problems with BIS monitor, we wont have it anymore.”

Drugs

Indications

No indication recorded.