drugset / Trial / NCT03286218
A Study of the Abuse Potential of Lasmiditan in Participants Who Are Recreational Drug Users
RandomizedCrossoverDouble-blindBasic science
Summary
The purpose of this study is to assess the abuse potential of study drug lasmiditan. Lasmiditan will be compared to a marketed benzodiazepine, alprazolam (positive control), as well as to placebo (dummy substance that looks like lasmiditan or alprazolam without any active drug) to determine the potential for drug abuse. The dosages will be in tablet form and will be taken orally (by mouth). This study will last about 55 days, including screening. Screening will occur within 28 days prior to qualification phase.
Timeline
- Start
- 2017-09-15
- Primary completion
- 2017-11-20
- Completion
- 2017-11-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Alprazolam | Small molecule | 2 mg | Oral |
| Subject | Lasmiditan | Small molecule | 100 mg | Oral |
| Subject | Lasmiditan | Small molecule | 200 mg | Oral |
| Subject | Lasmiditan | Small molecule | 400 mg | Oral |