drugset / Trial / NCT03293992
A Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7058584 Following 7 Days of Instillation of Eye Drops in Patients With Primary Open Angle Glaucoma or Ocular Hypertension
RandomizedParallel-groupDouble-blindTreatment
Summary
This is a Phase I, multi-center, randomized, adaptive, investigator/patient-masked, placebo-controlled, parallel multiple-ascending dose study (Part A) with an extension including up to two selected doses from Part A and latanoprost 0.005% as active comparator (Part B).
Timeline
- Start
- 2017-10-10
- Primary completion
- 2017-12-15
- Completion
- 2017-12-21
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Latanoprost | Small molecule | 0.005 % | Topical |
| Subject | RO7058584 | Unknown | 0.01 % | Topical |
| Subject | RO7058584 | Unknown | 0.1 % | Topical |
| Subject | RO7058584 | Unknown | 1 % | Topical |