drugset / Trial / NCT03299413
Use of Mesenchymal Stem Cells in Inflammatory Bowel Disease
NaSingle-groupOpen-labelTreatment
Summary
Scientists hypothesize that directly or parentally injecting Mesenchymal stem cells (MSCs) to affected areas will have a positive impact through reducing or abolishing intestinal inflammation in part via inhibition of neutrophil Myeloperoxidase (MPOx) activity. Inhibiting MPOx should modify disease progression as well as reduce colitis associated cancer risk.
Timeline
- Start
- 2017-06-05
- Primary completion
- 2019-11
- Completion
- 2020-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Wharton Jelly Mesenchymal stem cells | Cell therapy | 1.2e+08 cells | Intravenous |