drugset / Trial / NCT03299686

Study to Assess the Efficacy and Safety of CJM112 in Patients With Inadequately Controlled Severe Asthma

NCT03299686

Phase 2 Completed 118 enrolled Novartis Pharmaceuticals
RandomizedParallel-groupQuadruple-blindTreatment

Summary

An unmet medical need exists for patients with moderate and severe asthma who continue to demonstrate symptoms despite being on standard of care medications, and are not eligible for other biologic therapies developed or in development for T2-high(allergic/eosinophilic) asthma. The purpose of this study was to determine if CJM112, an anti-IL-17A antibody, displayed the clinical efficacy and safety profile to support further development in patients with inadequately controlled moderate to severe asthma with low IgE and low circulating eosinophil levels.

Timeline

Start
2017-11-06
Primary completion
2019-04-08
Completion
2019-07-08

Drugs

EvaluationDrugModalityDoseRoute
Subject CJM112 Monoclonal antibody 300 mg Subcutaneous

Indications