Pregabalin Effects on Hypotensive Anesthesia During Spine Surgery.

Summary

Elective lumbar spine surgical procedures are commonly performed under controlled hypotension during general anesthesia. That is beneficial to limit the intraoperative blood loss and transfusions and improves surgical field. Deliberate hypotension could be achieved via various medications but mostly associated with significant side effects. Pregabalin effectively augmented hypotensive anesthesia. The hypothesis is that Pregabalin 150 mg single preoperative dose may augment intraoperative deliberate hypotension that will be reflected on blood loss and nitroglycerin consumption.

Timeline

Start

2018-01-08

Primary completion

2018-03-30

Completion

2019-04-30

Drugs

Indications

No indication recorded.