drugset / Trial / NCT03301181
Phase 1 Study to Investigate Effect of Rifampin and Itraconazole on the Pharmacokinetics of BGB-3111 in Healthy Subjects
Non-randomizedParallel-groupOpen-labelBasic science
Summary
Phase 1 study in healthy subjects to determine the effect of rifampin (Part A) or itraconazole (Part B) on the pharmacokinetics of BGB-3111
Timeline
- Start
- 2017-09-18
- Primary completion
- 2017-11-07
- Completion
- 2017-11-13
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Itraconazole | Small molecule | 200 mg | — |
| Subject | Rifampicin | Small molecule | 600 mg | — |
| Subject | Zanubrutinib | Small molecule | 80 mg | Oral |
| Subject | Zanubrutinib | Small molecule | 320 mg | Oral |
Indications
No indication recorded.