drugset / Trial / NCT03304496

Subcutaneous Nitroglycerin to Facilitate Trans-radial Access.

NCT03304496 ↗

Phase 4 Suspended 1400 enrolled Instituto Nacional de Cardiologia Ignacio Chavez
RandomizedParallel-groupTriple-blindSupportive care

Summary

Femoral artery approach to perform coronary procedures is considered the standard technique for vascular access due to optimal catheter control, lower thromboembolic complications and immediate access due to the large diameter of the artery. Trans-radial approach has been shown to reduce major bleeding complications, vascular complications related to the site of puncture, including death from all causes, and to prevent post-procedure limb rest, greater comfort for patients, immediate ambulation, early discharge and reduction of costs. Previous studies have shown that intravenous, topical and intraarterial use of nitroglycerin produces vasodilation of the radial artery. Extravascular (subcutaneous) administration of nitroglycerin is extremely effective in restoring the radial pulse, and allows adequate cannulation.

Timeline

Start
2018-03-30
Primary completion
2019-03-30
Completion
2026-03-31

Outcome

Outcome not reported

Stopped: “The sample was not completed.”

Drugs

EvaluationDrugModalityDoseRoute
Subject Nitroglycerin Unknown 500 ug Subcutaneous