drugset / Trial / NCT03316872

Study of Pembrolizumab and Radiotherapy in Liver Cancer

NCT03316872 ↗

Phase 2 Terminated 18 enrolled University Health Network, Toronto
NaSingle-groupOpen-labelTreatment

Summary

This is a phase 2 study whose purpose is to assess the efficacy of the combination of pembrolizumab and stereotactic body radiotherapy (SBRT) in patients with advanced hepatocellular carcinoma (HCC) who have experienced disease progression after treatment with sorafenib.

Timeline

Start
2018-02-15
Primary completion
2024-02-15
Completion
2024-02-15

Outcome

Outcome not reported

Stopped: “The study was stopped due to the shift in systemic treatment paradigm for HCC precluding further enrolment.”

Drugs

EvaluationDrugModalityDoseRoute
Subject Pembrolizumab Monoclonal antibody 200 mg Intravenous