drugset / Trial / NCT03320447

Long-term Efficacy of Ablative Fractional Laser-assisted Photodynamic Therapy for Treatment of Lower Extremity Bowen's Disease

NCT03320447

Phase 1 Completed 60 enrolled Dong-A University
RandomizedFactorialTriple-blindTreatment

Summary

Er:YAG ablative fractional laser-assisted methyl aminolevulinate photodynamic therapy (AFL-PDT) has shown significantly higher efficacy and a lower recurrence rate at 12 months than methyl aminolevulinate photodynamic therapy (MAL-PDT) for treatment of Bowen's disease (BD). However, long-term follow up data are not available.

Timeline

Start
2011-10-30
Primary completion
2016-10-30
Completion
2017-10-19

Drugs

EvaluationDrugModalityDoseRoute
Subject methyl aminolevulinate Small molecule 16 % Topical
Background Lidocaine-Prilocaine Unknown 5 % Topical