drugset / Trial / NCT03320629

A Study of Apatinib Plus Radiotherapy and S-1 for Treatment of Refractory or Metastatic Esophageal Squamous Cell Carcinoma

NCT03320629 ↗

Phase 2 Terminated 7 enrolled Hebei Medical University Fourth Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to assess the efficacy and safety of patients who receive apatinib plus radiotherapy and S-1 for treatment of refractory or metastatic esophageal squamous cell carcinoma.

Timeline

Start
2017-11-01
Primary completion
2017-11-01
Completion
2018-12-31

Outcome

Outcome not reported

Stopped (Enrollment): “This study was voluntarily terminated after investigator assessment, with no safety concerns identified related to the trial intervention or procedures. The primary reason for termination was difficulty in patient recruitment.”

Drugs

EvaluationDrugModalityDoseRoute
Subject Rivoceranib Small molecule 500 mg Oral
Subject S-1 Small molecule 40 mg Oral
Subject S-1 Small molecule 60 mg Oral