drugset / Trial / NCT03332732
VNRX-5133 Drug-Drug Interaction in Healthy Adult Volunteers
Phase 1
Completed
42 enrolled
Venatorx Pharmaceuticals, Inc.
National Institute of Allergy and Infectious Diseases (NIAID) · collab
RandomizedSequentialDouble-blindBasic science
Summary
This is a 2-part, drug-drug interaction study to evaluate potential PK interactions after single doses in Part 1 and multiple doses in Part 2. In Part 1, subjects will receive single dose of 5 treatments in a cross-over design; in Part 2 subjects will receive treatment for 10 days.
Timeline
- Start
- 2017-10-24
- Primary completion
- 2017-12-20
- Completion
- 2017-12-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cefepime | Small molecule | — | — |
| Subject | Metronidazole | Small molecule | — | — |
| Subject | taniborbactam | Other / unclassified | — | — |