drugset / Trial / NCT03332732

VNRX-5133 Drug-Drug Interaction in Healthy Adult Volunteers

NCT03332732

RandomizedSequentialDouble-blindBasic science

Summary

This is a 2-part, drug-drug interaction study to evaluate potential PK interactions after single doses in Part 1 and multiple doses in Part 2. In Part 1, subjects will receive single dose of 5 treatments in a cross-over design; in Part 2 subjects will receive treatment for 10 days.

Timeline

Start
2017-10-24
Primary completion
2017-12-20
Completion
2017-12-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Cefepime Small molecule
Subject Metronidazole Small molecule
Subject taniborbactam Other / unclassified