drugset / Trial / NCT03340896
Trial of Laryngeal Preservation Comparing Induced CT Followed by RT vs CT Concomitant to RT
RandomizedParallel-groupOpen-labelTreatment
Summary
This study compare the survival without laryngeal dysfunction 2 years after the end of treatment, obtained by chemotherapy followed by radiotherapy or chemotherapy with cisplatin administrated during radiotherapy.
Timeline
- Start
- 2015-06-25
- Primary completion
- 2028-10
- Completion
- 2028-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cisplatin | Other / unclassified | 75 mg/m2 | Intravenous |
| Subject | Cisplatin | Other / unclassified | 100 mg/m2 | Intravenous |
| Comparator | Docetaxel | Small molecule | 75 mg/m2 | Intravenous |
| Comparator | fluorouracil | Small molecule | 750 mg/m2 | — |