drugset / Trial / NCT03343509

Topical Versus Oral Metronidazole Following Excisional Haemorrhoidectomy

NCT03343509 ↗

Phase 4 Completed 120 enrolled University of Auckland, New Zealand
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This study aims to determine if topical metronidazole reduces pain more than oral metronidazole following excisional haemorrhoidectomy. The trial will be a multi-centered, patient and investigator blinded superiority trial with two parallel groups and a primary outcome of pain scores during 14 days after surgery. Group A will receive oral metronidazole and placebo cream. Group B will receive placebo tablets and topical metronidazole cream.

Timeline

Start
2019-03-11
Primary completion
2020-02-01
Completion
2020-02-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Metronidazole Small molecule 10 % Oral
Subject Metronidazole Small molecule 400 mg Oral

Indications