drugset / Trial / NCT03343509
Topical Versus Oral Metronidazole Following Excisional Haemorrhoidectomy
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This study aims to determine if topical metronidazole reduces pain more than oral metronidazole following excisional haemorrhoidectomy. The trial will be a multi-centered, patient and investigator blinded superiority trial with two parallel groups and a primary outcome of pain scores during 14 days after surgery. Group A will receive oral metronidazole and placebo cream. Group B will receive placebo tablets and topical metronidazole cream.
Timeline
- Start
- 2019-03-11
- Primary completion
- 2020-02-01
- Completion
- 2020-02-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Metronidazole | Small molecule | 10 % | Oral |
| Subject | Metronidazole | Small molecule | 400 mg | Oral |