drugset / Trial / NCT03344159

Spironolactone Therapy in Chronic Stable Right HF Trial

NCT03344159

Phase 4 Completed 15 enrolled Ottawa Heart Institute Research Corporation
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to evaluate the safety, tolerability and mechanistic effects of spironolactone, an aldosterone receptor antagonist, on sympathetic nervous system activity and right heart function and remodeling in patients with chronic right heart failure.

Timeline

Start
2018-04-01
Primary completion
2022-08-30
Completion
2024-05-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Spironolactone Small molecule 50 mg