Glutamatergic Modulation to Facilitate the Behavioral Treatment of Cocaine Use Disorders

Summary

Changes in the communication of glutamate from one brain structure to another are important in the development of therapy for cocaine use disorders. Our preliminary investigations suggest that drugs that affect glutamate exchange may be effective at promoting and maintaining individuals' abstinence from cocaine. The purpose of this randomized, double-blind, controlled trial is to test various glutamate modulators in conjunction with motivational enhancement therapy (MET) and mindfulness based relapse prevention (MBRP) for cocaine use disorders.

Timeline

Start

2017-10-01

Primary completion

2024-12-31

Completion

2024-12-31

Outcome

Outcome not reported

Stopped (Business): “Funding”

Drugs

Indications